Abstract

ROLE OF COQ10 SUPPLEMENTED TO THAWING SOLUTION IN IMPROVEMENT HUMAN SPERM PARAMETERS POST-CRYOPRESERVATION

Prof. Dr. Muhammad Baqir M-R Fakhrildin* and Mohammad Hassan Abdullah

ABSTRACT

Background: Cryopreservation techniques are highly developed field of Assisted Reproductive Technologies (ARTs) to help infertile couples to overcome infertility. Coenzyme Q10 (CoQ10) is a vitamin – like substance is present in most eukaryotic cell, and produced in the mitochondria primarily. Objective: To study the effects of CoQ10 supplemented to thawing solution on sperm parameters post- cryopreservation technique. Materials and Methods: One hundred and eight males were participated in this study. The mean age for all males included in this study was (29.94 ± 0.65) years and duration of infertility was 2-14 years. Semen samples were collected and seminal fluid analysis was done according to WHO (2010] All groups contain 1mL from semen sample mixed with 0.7 mL of cryopreservation solution. All groups after thawing were divided into 3 subgroups (GA: control group; without honey bee), (GB: contain 5 μm from CoQ10) and (GC: contain 10 μm] Results: There was significant increase (P

Keywords: Human, Sperm, Infertility, Cryopreservation, Coenzyme Q10.