Abstract

FORMULATION AND EVALUATION OF POLY HERBAL ANTI DIABETIC TABLETS

*Himaja N., Ashok Kumar Appapurapu and Bharat Kumar B.

ABSTRACT

Objective: The main objective of the work is to formulate and evaluate poly herbal anti diabetic tablet for medicinal purpose. Materials and methods: Azadirachta indica, Mangifera indica, Ocimum sanctum leaves were collected from the local area, dried, powdered and extracted with ethanol separately and stored for further use. Tablets were prepared after preformulation studies and tablets were evaluated by using Weight variation, Hardness, Friability, Thickness and Disintegration Time. Results: Prepared granules by wet granulation method were performed preformulation studies based on the preformulation studies powder flow properties are good and Weight variation was ± 5%, Hardness, Friability are respectively 3.5 ± 0.43 kg/cm2, 0.58 ± 0.05%. Thickness was measured as 3 ± 0.02 mm and Disintegration time 6 ± 0.32 min are good. Discussion and Conclusion: Now a day’s Herbal medicines plays major role in the treatment than allopathic medicines because of less toxicity. Azadirachta indica, Mangifera indica, Ocimum sanctum ethanolic extracts were used to formulate tablets. Based on the results it is clearly concluded that the prepared formulation of poly herbal antidiabetic tablets and evaluations are good.

Keywords: poly herbal, anti diabetic tablet, Azadirachta indica, Mangifera indica, Ocimum sanctum, Disintegration time.