Abstract

IN VITRO DNA PROTECTIVE POTENTIAL OF P. HYSTEROPHORUS LEAF EXTRACT

Bhanu Pratap Singh Parihar*, Bushra Khan and Vipul Keerti Sharma

ABSTRACT

The present work reports the effect of P. hysterophorus leaf phytoconstituents (flavonoids, phenolics, tannin and phytic) as DNA protection assay. These Phytochemicals are proved as potent anticancerous and antioxidant capacity. Dried leaf samples were extracted with methanol fraction showed noticeable amount of these phytochemicals. On evaluating the effect of these phytochemicals as DNA protective assay, damaged caused in vitro using Fenton’s reagent. Present study showed the increasing concentration of methanolic extract causes protective effect on DNA damage. So from this finding we concluded that P. hysterophorus leaf have considerable phytoconstituents which can be considered as valuable asset as nutraceuticals ingredients for treatment of various diseases.

Keywords: DNA protection assay, Phenolics, Flavonoids, Phytic acid, Tannins, Phytochemicals.