Abstract

THE DRUG UTILIZATION OF CEPHALOSPORINS IN A TERTIARY CARE HOSPITAL

Dr. Bandari Kiran*, Dr.Md.Abuzar Ghufran, Dr. T. S. Sunil Kumar,
Dr.D.Shravan Kumar

ABSTRACT

utilization research can increase our understanding of how drugs are being used to estimate the numbers of patients exposed to specified drugs within a given time period. Such estimates may either refer to all drug users, regardless of when they started to use the drug (prevalence), or focus on patients who started to use the drug within the selected period (incidence). It can describe the extent of use at a certain moment and/or in a certain area (e.g. in a country, region, community or hospital) The mean duration of hospitalization among the study population was 6.25 days. 121 cephalosporins prescribed out of 115 patients. Majority of patients were 26 belonged to age group 61-70 (34.21%). used generic (22) 18.18% and brand drugs was (99) 81.82%. route of administration of cephalosporin’s were prescribed more commonly in injection form (105) 86.78%, mainly second (25) 20.66% and third generation drugs were (96) 79.34%. Cefoperazone +sulbuctum (47) (38.84%) and cefixime (40) 33.06% were the commonly prescribed third generation cephalosporins. Fourty one (41) patients were received cephalosporins along with co-prescribed other antibiotics in the treatment. The majority of co-prescribed other antibiotics were Metronidazole prescribed in fifteen (15) patients 36.59%. The majority of patients were utilized cephalosporins in Hepatology thirty (30) patients with 26.09%, According to the ATC classification the overall direct costs from use of cephalosporins and other antibiotics consumption was 4, 71,758.4 lakhs of rupees in 719 bed days and the (Daily Drug Dose) DDD/100BD was 6577.64 rupees consumed in hospital stay.

Keywords: Cephalosporins utilization, Drug utilization research, Drug utilization and review, rational use of drug.