Abstract

ANTI ULCER ACTIVITY OF PANDANUS FASCICULARIS (LAM.) ON ETHANOL INDUCED ULCER IN WISTAR ALBINO RATS

Abirami J., Sathya P., Joshi Eminal J. and Brindha P.*

ABSTRACT

Pandanus fascicularis Lam (Pandanaceae), widely growing perennial climber, has been used in traditional medicine for treating many aliments. The objective of the present study was to evaluate the effects of aqueous extract of Pandanus fasicularis Lam leaves on Ethanol induced gastric ulcer. Animals were divided in to five groups. Group I treated as Normal control. Group II treated as disease control (1ml Ethanol).Group III treated as standard control, (80mg Ranitidine/ Kg.bw), Group IV and Group V treated as (aqueous leaf extract of Pandanus fascicularis (Lam.), (100mg and 200 mg respectively). Preliminary phytochemical screening of the plant extract of Pandanus fasicularis Lam. revealed the presence of steroids, saponin, sterol, alkaloids, quinone, phenol, coumarin and glycosides. The Extract at dose 100mg/kg b.w and 200mg/kg b.w. significantly (P

Keywords: Pandanus fascicularis (lam.), Ulcer index, Total acidity, ALT, AST.