Abstract

ANTIBACTERIAL ACTIVITY OF SOME PLANTS AGAINST DRUG RESISTANT NEONATAL SEPSIS CAUSING BACTERIA

Anchal Agarwal*

ABSTRACT

The study was undertaken to investigate the organisms responsible for sepsis in the Neonatal Unit at S.V.B.P. Hospital, Meerut Uttar Pradesh, to determine their resistance pattern to antibiotics. A total of 120 neonates having one or more signs of sepsis as respiratory distress, jaundice, cyanosis and lethargy and aged from 0 to 28 days were included in this study. A blood sample was taken each subject, cultured and then antibacterial susceptibility test was performed for isolates. 80 (66.66%) cases yield positive cultures. The gram negative bacteria constituted 57.5% of the total isolates, from which E. coli was the predominant pathogen (27.5%) followed by Klebsiella pneumoniae (17.5%) and Pseudomonas aeruginosa (12.5%). The gram positive bacteria constituted 42.5% of the total isolates, from which S. aureus was the prominent pathogen (21.25%) followed by Enterococcus spp. (13.75%) and Coagulase Negative Staphylococci (7.5%).

Keywords: Enterococcus sp, E. coli, Klebsiella pneumonia, Pseudomonas aeruginos Staphylococcus, Medicinal plants and Antibacterial Activity.