Abstract

A REVIEW ON LEPTOSPIROSISA REVIEW ON LEPTOSPIROSIS A REVIEW ON LEPTOSPIROSIS A REVIEW ON LEPTOSPIROSISA REVIEW ON LEPTOSPIROSIS A REVIEW ON LEPTOSPIROSIS A REVIEW ON LEPTOSPIROSIS A REVIEW ON LEPTOSPIROSISA REVIEW ON LEPTOSPIROSISA REVIEW ON LEPTOSPIROSIS

Suvarna P. Ningal*, Manoj B. Kothule, Nilesh Y. Jadhav, Sagar D.Kadam, Yogesh S. Katare, Sandip A. Hapse

ABSTRACT

Leptospirosis is a bacterial disease caused by bacteria from genus of Leptospira. In 1886 Adolf Weil described Leptospirosis as disease entity. Leptospirosis has many different names including: "7-day fever", "harvest fever", "field fever", "canefield fever", "mild fever", "rat catcher's yellows", "Fort Bragg fever", and "pretibial fever". Leptospires are bacteria which can be either pathogenic or saprophytic Leptospirosis are transmitted in humans by contact with soil or water contaminated with urine of certain infected animals like rodents, dog and cattle. This bacteria enters in human body through abrasion in the skin or through conjunctiva. It occurs worldwide but most common areas are tropical and subtropical areas with high rainfall. Mild symptoms include flu, headaches and chill but in severe cases organ failure and bleeding, dengue fever and other haemorrhagic diseases. Leptospirosis can be treated with antibiotics like penicillin G, ampicillin, amoxicillin and Doxycycline. In more severe cases cefotaxime preferred. Most patients can recover completely hence fatality rate is low i.e. 5 to 30%. No human vaccination is available only prevention and treatment is effective.

Keywords: Leptospira, Weil’s disease, Cefotaxime, Saprophytic.