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EVALUATION OF WOUND HEALING POTENTIAL OF CRUDE LEAVE EXTRACTS OF CROTALARIA PALLIDA AITON. IN WISTAR RATS.
Sangram Keshari Panda*, Debajyoti Das, Niraj. K. Tripthathy, S.R.Mishra, R.P.Padhy
ABSTRACT The present study was an attempt to investigate the wound healing potential in two different types of wound models in albino rats viz., incision and excision. of various extracts of Crotalaria pallida leave.The different crude extracts such as ethanol, ethyl acetate, n-butanol and petroleum ether are obtained by successive soxhlet extraction The ethanolic extract showed significant increase in wound contraction and formation of scar in excision wound model. The extract showed significant increase in the breaking strength of resutured incision wound as compared to control group(p<0.05). The result of the present study indicate that ethanolic extract of C.pallida has more significant wound healing property than the other three extracts in excision and incision wound model. Keywords: Crotalaria pallida; Excision and incision wound model. [Download Article] [Download Certifiate] |