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FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET OF GLIMIPRIDE
Pragya Niranjan*,Dr. Sunil prajapati ,Anju Varma
ABSTRACT
In the present work, fast dissolving tablets of glimipride were prepared by direct compression method with a view to enhance patient compliance. Two superdisintegrants viz, crospovidone and croscarmellose sodium (4%, 5%, 6%) with different binders viz, pvp k-30 and pregelatinized starch (3%) were used. The prepared batches of tablets were evaluated for hardness, friability, weight variation, disintegration, wetting time, drug content and in vitro dissolution studies. Based on evaluating parameters, Formulation prepared by using 5% croscarmellose sodium with 3% PVP K30 was selected as Keywords: Fast Dissolving Tablets, Glimipride, Superdisintegrants, Direct Compression. [Download Article] [Download Certifiate] |