Abstract

ANALYSIS OF NOOTROPIC EFFECT OF ETHANOLIC EXTRACT OF BETA VULGARIS L. ROOTS IN AGE INDUCED AMNESIA IN SWISS ALBINO MICE

Ahuja D.

ABSTRACT

Learning refers to the process by which brain acquires new information about the events occurring in the surroundings and recalling of information is referred to as memory. Memory comprises of registration, consolidation and retrieval. Now a days a prevalence of neurodegenerative disorders is increasing day by days. Beta Vulgaris L. (Beet) is the abundantly available plant in Indian Subcontinent, the antioxidant, anti-inflamatory & hepatoprotective potential of Beta Vulgaris L. has been established but nootropic potential of the plant has not been explored the present study is designed to evaluate the nootropic potential of Beta Vulgaris L. roots extract. In this study Hydroalcoholic Extract of Beta Vulgaris L. Roots was evaluated for Nootropic potential by using Morris Water Maze model. The present study has been designed to investigate the effect of Hydroalcoholic Extract of Beta Vulgaris L. Roots in Age induced experimental amnesia in mice. The mice were divided into groups i.e Control Group, Normal Saline Treated Group, Aged Group, Aged + Metrifonate Treated Group, Aged + Piracetam Treated Group & Aged + Beat Root 250,500,1000 Mg/Kg Treated Groups. On analysis of results it was found that the extract treated animals showed increased Escape Latency Time spent in search of missing platform in day 5 in Morris Water Maze. This suggests that Hydroalcoholic Extract of Beta Vulgaris L. Roots shows significant Nootropic activity.

Keywords: Beta Vulgaris L., Nootropic, Morris Water Maze, Escape Latency Time.