Abstract

PHARMACEUTICAL MINI TABLETS, ITS ADVANTAGES AND DIFFERENT ENTERIC COATING PROCESSES

A. Mounika*, B. Sirisha and V. Uma Maheshwar Rao

ABSTRACT

The objective of controlled drug delivery systems is to reduce the frequency of the dosing and to increase the effectiveness of the drug by localization. In oral controlled drug delivery systems, multiple unit dosage forms (MUDFs), like granules, pellets and mini tablets effectively control the release of the drug when compared to single unit dosage forms (SUDFs) like tablets and capsules. Among all MUDFs, mini-tablets offer several advantages like they can be manufactured relatively easily, they do not require any solvent for their production, can be coated reproducibly, and also requires less coating material. Also, there is a great flexibility during their formulation development. In this context, last few decades have witnessed some major advancement. This review emphasizes the various advantages of mini- tablets, formulation possibilities, general evaluation tests, and brief insight to marketed drugs.

Keywords: Biphasic delivery systems, compressed mini-tablets, encapsulated coated systems, Granules, Mini-tablets, Pellets.