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Abstract

COMPARATIVE STUDY OF THE GASTROKINETIC EFFECTS OF ERYTHROMYCIN AND AZITHROMYCIN IN HEALTHY SUBJECTS: SONOGRAPHIC STUDY.

Ugwu AC, Agwu KK, *Umeh EC, Imo AO and Ohuegbe C

ABSTRACT

AIM: The purpose of this study was to investigate the comparative gastrokinetic effects of erythromycin and azithromycin in apparently healthy subjects. METHODOLOGY: Ultrasonographic evaluation of changes in gastric antral areas were undertaken in 24 subjects after a liquid meal at five minutes interval for thirty minutes. These were performed in pre-prandial states in a cross over method between erythromycin and azithromycin ingestion. The gastric antral areas were calculated as compared used paired t test as a measure of relative motilities induced by these drugs. P

Keywords: Erythromycin, Azithromycin, gastrokinesis, ultrasonography.


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