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Abstract

PREFACE OF BIOMARKERS IN RECENT ASPECTS OF CANCER: A REVIEW

Tanushree Roy1* and Saikat Ghosh2

1Department of Pharmacology, Gupta College of Technological Sciences, Asansol-713301, West Bengal, India.
2Department of Pharmaceutical Technology, Jadavpur University, Kolkata-700032, West Bengal, India.

ABSTRACT

In recent years, cancer biomarkers provide a great opportunity for improving the management of cancer patients by enhancing the efficiency of detection and efficacy of treatment. Biomarkers include a broad range of biochemical entities, such as nucleic acids, proteins, sugars, lipids, and small metabolites, cytogenetic and cytokinetic parameters as well as whole tumor cells found in the body fluid. Biomarkers used for screening, monitoring, diagnosis and treatment optimization must have the potential to improve patient outcomes and reduce costs associated with inappropriate (or suboptimal) therapeutic regimens. Each biomarker with its relative advantages provides a wide range of multiple therapeutic alternatives currently available. This review provides a brief account on various biomarkers that would fill the gap currently existing between basic research and clinical use of advanced diagnostics.

Keywords: epigenetic, mTOR, biomarker, antigen, telomerase, PIN.


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