EVALUATION OF ANTI-DIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF DESMOSTACHYA BIPINNATA ON ALLOXAN INDUCED DIABETES IN RATS
Ravindra Babu Sajja* and Sraddha Bhaskari D
ABSTRACT
The present study was carried out to evaluate the antidiabetic activity
of ethanolic extract of Desmostachya bipinnata whole plant (EDB) in
alloxan induced diabetic rat model in which the rats were treated with
alloxan (150mg/kg, i.p). The study was carried out on a 14 day
protocol and the parameters monitored were blood glucose,
triglycerides, cholesterol, SGOT, SGPT, ALP, creatinine, urea, uric
acid, body weights and oral glucose tolerance were evaluated.. Our
study clearly indicated that the ethanolic exract of Desmostachya
bipinnata whole plant showed significant antidiabetic activity at both
doses (200mg/kg and 400mg/kg) as significant decrease (P
Keywords: Desmostachya bipinnata, Alloxan, SGOT, Cholesterol.
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