Abstract

EFFICACY OF CEFIXIME IN THE TREATMENT OF URINARY TRACT INFECTION

Mukesh Kumar Chaudhary*, Ghyanshyam Pandey, Mahendra Godar, Ramesh Gautam and Subash Gurung

ABSTRACT

Introduction: A urinary tract infection (UTI) (also known as acute cystitis or bladder infection) is an infection that affects part of the urinary tract. When it affects the lower urinary tract it is known as a simple cystitis (a bladder infection) and when it affects the upper urinary tract it is known as pyelonephritis (a kidney infection). Symptoms from a lower urinary tract include painful urination and either frequent urination or urge to urinate (or both), while those of pyelonephritis include fever and flank pain in addition to the symptoms of a lower UTI. Bacteria are the main cause for UTI. Cefixime is an antibiotic useful for the treatment of a number of bacterial infections. It is a third generation cephalosporin. Cefixime, when given orally is well absorbed and has a long plasma half life (3-4 hrs) and a good therapeutics index in a variety of infection. Objective: The aim of this study was to determine the Efficacy of Cefixime in Urinary Tract Infection in the different hospitals and polyclinic of Rupandehi districts of Nepal. Methodology: A prospective study was conducted in Crimson Hospital, Manigram, Rupandehi, Grace Polyclinic, Bhalwari, Rupandehi and Aaram Polyclinic, Kotihawa, Rupandehi. Patient information was obtained by interviewing the patient and from their lab report. Result: Out of 65 patients, 3 patients did not arrive during the follow up procedure while 61 patients recovered completely with Cefixime showing efficacy of 98.38%. Conclusion: Cefixime was effective in the treatment of UTI.

Keywords: Urinary Tract Infection, Cefixime, Urine culture, E.coli.