Abstract

EFFECT OF MARKER ENZYMES IN UROLITHIATIC RATS TREATED WITH ENSETE SUPERBUM ROXB. SEED EXTRACT

Jisha Mol .G* and Shamina .S

ABSTRACT

Medicinal plants constitute an effective source of both traditional and modern medicines. Herbal medicine has been revealed to have valid utility and about 80% rural population depends on its efficacy for their primary health care. The research is lead to the advance usage of indigenous herbal medicines for Urolithiasis. Medicinal plants can be valuable therapeutic resources. The study enlightens the effect of Ensete superbum Roxb. ethanolic seed extract in the urolithiatic male albino rats. The administration of Ethylene glycol (0.75%) to the male albino rats were resulting the urolithiasis to the rats. The induction of ethylene glycol is of 30 days and after that the analysis of serum and kidney marker enzymes. The level of marker enzymes AST, ALT, ACP and ALP was showing a decreased level in the kidney because of the cell destruction of tissues caused by urolithiasis. In serum, the level of these enzymes were elevated by the release of enzymes from the organ. It concludes that the treatment with ethanolic seed extract of Ensete superbum Roxb. is capable of counteracting the urolithiasis.

Keywords: Urolithiasis, Ethylene Glycol, Ensete superbum (Roxb).