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GREEN BIOSYNTHESIS OF SILVER NANOPARTICLES FROM ELETTARIA CARDAMOMUM (SEED) AND ITS IN VITRO CYTOTOXIC ACTIVITY
Venugopal Krishnan*1, Rajagopal Kalyanaraman, Gracy Fathima, Khalefathullah Sheriff, Mohamed Illiyas, Hilal Ahmad Rather, Ramar Thangam2and Thenmozhi
ABSTRACT The green synthesis of silver nanoparticles (AgNPs) using Elettaria cardamomum (seed) extract and its cytotoxicity activity against Hep-2 cell line were reported. The synthesized AgNPs using Elettaria cardamomum extract was preliminarily confirmed by UV– visible spectroscopy and it was further characterized by FT-IR. The UV–visible spectrum showed an absorption peak at 456 nm which reflects surface plasmon resonance (SPR) of AgNP. the green synthesized AgNPs exhibited a dose-dependent cytotoxicity against Human Larynx Carcinoma cancer(Hep-2) and the inhibitory concentration (IC50) were found to be 51μg/ml. Furthermore, the synthesized SNPs shows significant anticancer activity against Hep-2 cancer cell line. Keywords: Silver Nanoparticle, Anticancer, Elettaria cardamomum. [Download Article] [Download Certifiate] |