Abstract

SUSTAINED RELEASE INJECTABLE FORMULATIONS: ITS RATIONALE, RECENT PROGRESS AND ADVANCEMENT.

Nikita P. Karode*, Vipul D. Prajapati, Himanshu K. Solanki, Girish K. Jani

ABSTRACT

Oral drug delivery plays a prominent role among all the other routes of drug delivery. But nowadays in our fast going world, injectable drug delivery helps out to get instant results. Parenteral route is mostly avoided by the patients due to its pain while administering the drug. To get rid of patient incompliance in the case of frequent dosing, the concept of sustained release parenteral formulation was discovered. The concept benefits not only rapid onset of action but also helps in reducing frequent dosing and maintains a proper systemic level of drug. This article will briefly cover current options for extended release injectable drug delivery system consisting microsphere, implants, suspension, emulsion, liposome, noisome, protein and peptides.

Keywords: injectable, microsphere, liposome, implants.