A REVIEW ON BHAISHAJ AVCHAARANA KAAL (TIME OF DRUG ADMINISTRATION) WITH SCIENTIFIC BASIS AND CONCEPT OF CHRONO-PHARMACOLOGY
Dikshit Manishha*, Garg Puneet Kumar and Saxena G. K.
ABSTRACT
Bhaishaj Avchaaran Kaal is an important phenomenon while treating a
disease Bhaishaj Sevan Kaal is mainly explained by various factors
such as Dosha, Dooshya, Roga and Bala of Rogi etc. Chronos is a
greek word which means time i.e. chronobiology being the study of
alterations of each organism’s temporal structure under various
conditions and Chronopharmacology is the branch dealing with the
pharmacologic aspects of Chronobiology. Circadian rythms are found
in all organisms, so the different aushadhi avchaaran kaal are defined
according to the biological clocks. The final goal of chikitsa(treatment)
is to obtain equilibrium in Doshas and Dhatus, which is only by giving
Aushadhi in a proper time. This comprehensive concept evolves many
questions about bhaishaj avchaaran kaal, their indications and contra indications, their action
on body(pharmacokinetics) and how the body acts against drug (pharmacodynamics). The
present review is an attempt to answer all these questions.
Keywords: Bhaishaj Avchaaran kaal, Chronopharmacology,Circadian Rhythm, Roga, Rogi Bala.
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