Abstract

IN-VIVO NEPHROPROTECTIVE POTENTIAL FROM LEAVES EXTRACTS OF ANDROGRAPHIS PANICULATA

K. Padmalochana* and M.S. Dhana Rajan

ABSTRACT

Nephrotoxicity is the third most common problemof the renal system. Medicinal plants potentially useful for the treatment of severe renal disorders. In the present study, the effect of aqueous, ethanol and acetone extract of Andrographis paniculata leaves was evaluated by pretreating three groups of rat animals. Renal failure was induced by antibiotic drug gentamicin which was orally administered to group II animals and untreated control model was maintained. After oral administration for 10 days, serum levels of urea, uric acid, creatinine and total protein were assayed. All the biochemical parameters were significantly controlled (p

Keywords: Kidney, A. paniculata, Herbal medicine.