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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

INVESTIGATION ON ARISTOLOCHIA INDICA - IMMUNOMODULATOR ACTIVITY

G.K.Mallaiah*, K. Thirupathi and G. Krishna Mohan

ABSTRACT

The immunomodulator activity of Aristolochia indica was carried out in mice and rats. The assessment of immunomodulatory activity was carried out by various hematological and serological tests. In this study, various doses (100, 200 and 400mg/kg body weight/day) of the methanolic extract and its bioactive fractions of the roots of the plant were administered in mice and rats. Of these, Ethyl acetate fraction showed significant activity and increased phagocytic response, both cellular and humoral antibody response. The activity reported was dose dependent and test extract posses promising immuno-stimulant properties.

Keywords: Aristolochia indica, rats, mice, hematological and serological tests.

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