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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

SYNTHESIS AND CHARACTERIZATION OF 5-(SUBSTITUTED PHENYL)- 2- FURFURALDEHYDES FROM SUBSTITUTED ANILINES

*Munendra Mohan Varshney¹, Asif Husain², Versha Parcha³

¹Faculty of pharmacy, Uttrakhand Technical University, post office chandanwadi, Prem Nagar, suddhowala, Dehradun-248007 (U.K), India

²Dept. of pharmaceutical chemistry, Jamia Hamdard University, New Delhi, India

³Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences, Dehradun (U.K), India

ABSTRACT

A new method for the synthesis of substituted furfuraldehyde is detailed. Reaction was carried out by substituted aniline to substituted diazonium chloride salt at 0o C in the presence of sodium nitrite further Meerwin arylation reaction of diazonium chloride salt of substituted aniline with furfuraldehyde forms the different 5-( substituted phenyl)- 2-furfuraldehydes (IVa-k). The physical and spectral data of the synthesized compounds were obtained by melting point apparatus, IR, 1H NMR spectroscopy.

Keywords: Furfuraldehyde, Meerwin arylation, substituted anilines.

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