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SYNTHESIS AND CHARACTERIZATION OF 5-(SUBSTITUTED PHENYL)- 2- FURFURALDEHYDES FROM SUBSTITUTED ANILINES
*Munendra Mohan Varshney1, Asif Husain2, Versha Parcha3
1Faculty of pharmacy, Uttrakhand Technical University, post office chandanwadi, Prem Nagar, suddhowala, Dehradun-248007 (U.K), India
2Dept. of pharmaceutical chemistry, Jamia Hamdard University, New Delhi, India
3Sardar Bhagwan Singh Post Graduate Institute of Biomedical Sciences, Dehradun (U.K), India
ABSTRACT
A new method for the synthesis of substituted furfuraldehyde is detailed. Reaction was carried out by substituted aniline to substituted diazonium chloride salt at 0o C in the presence of sodium nitrite further Meerwin arylation reaction of diazonium chloride salt of substituted aniline with furfuraldehyde forms the different 5-( substituted phenyl)- 2-furfuraldehydes (IVa-k). The physical and spectral data of the synthesized compounds were obtained by melting point apparatus, IR, 1H NMR spectroscopy. Keywords: Furfuraldehyde, Meerwin arylation, substituted anilines. [Download Article] [Download Certifiate] |