Abstract

BIOMEDICAL APPLICATION OF MAGNETIC NANOPARTICLES FOR CANCER TREATMENT

Z. N. Kashmiri*

ABSTRACT

Cancer is described as the most hazardous class of disease describing a cluster of cells undergoing uncontrolled growth in the body. Over the last decade major advances have been made in the treatment of cancer. Radiation and chemotherapy are the traditional ways for cancer treatment but the toxic drug molecules do not act selectively to cancer cells and as such a enormous range of undesirable side effects have been experienced. Nano-sized formulations of cytotoxic agents have proved to passively target different cancer and promote increased drug efficacy due to the accumulation via enhanced permeability and retention resulting in deeper drug penetration. Nanoparticles with easily modified surfaces have been investigated extensively in recent years and play a pivotal role in biomedicine. Recently magnetic nanoparticles have been increasingly explored for clinical applications, such as drug delivery, magnetic resonance imaging and magnetic fluid hyperthermia for diagnosis and cancer therapy. This article highlights the application of magnetic nanoparticle in cancer treatment.

Keywords: Radiation, chemotherapy, magnetic nanoparticle, biomedicine.