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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

DOCETAXEL-INDUCED CHANGES IN CHOLESTEROL PROFILE: PROTECTIVE ROLE OF NARINGENIN AND NARINGIN

Dr. Supratim Ray*

ABSTRACT

The study was designed with an aim to evaluate the protective effects of naringenin and naringin on docetaxel-induced changes in cholesterol profile in vitro. Goat blood was used as lipid source for the model. In the cholesterol profile total cholesterol (TC) and high density lipoprotein (HDL) cholesterol content of goat blood was determined. The study reveals that docetaxel has the induction capacity to produce changes in cholesterol profile. It was also noticed that naringenin / naringin had the capacity to inhibit docetaxel-induced changes in cholesterol profile. Interpretation of the results is supported by analysis of variance and also by statistical multiple comparison analysis using least significant different procedure.

Keywords: Docetaxel, Naringenin, Naringin, Total cholesterol, HDL.

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