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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY OF VERNONIA ANTHELMINTICA (L.) WILLD. SEED EXTRACTS

Ratnam KV, Bhakshu L.M and Venkata Raju RR*

ABSTRACT

anthelmintica (L.) Willd. is a potential medicinal plant and the seeds were used for many human ailments in the Ayurveda, an Indian system of medicine. Ethyl acetate and ethanol extracts obtained from V. antihelminca (VA) seeds were evaluated for phytochemical and antimicrobial activity. The phytochemical screening of the tested extracts showed positive reactions towards the presence of flavonoids, alkaloids, coumarins and steroids. Antimicrobial study revealed that, the ethyl acetate extract exhibited strong and concentration dependent activity against the gram negative bacteria E. coli and Klebsiella pneumonia. Ethanol extract exhibited faint activity against all the test pathogens at 250 and 500 μg/disc. In conclusion, V. anthelminca seed extracts showed positive therapeutic effects against human pathogenic organisms and is a good source of natural antibiotics.

Keywords: Vernonia anthelmintica, seed extracts, antimicrobial activity.

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