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Abstract

STUDY OF ANTICANCER AGENTS FROM MEDICINAL PLANTS

Harish Kumar P and Karpagam N*

Department of biotechnology, Sri Venkateswara College of Engineering, Sriperumbudur- 602105, Tamil Nadu, India.

ABSTRACT

Cancer is one of the most common devastating disease affecting millions of people per year. Plant derived agents are being used for the treatment of cancer. Several anticancer agents including taxol, vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, and etoposide derived from epipodophyllotoxin are in clinical use all over the world. A number of promising agents such as flavopiridol, roscovitine, combretastatin A-4, betulinic acid and silvestrol are in clinical or preclinical development. These anti-cancer compounds have been found to be clinically active against various types of cancer cells. Further research in this area may lead to better treatment of cancer.

Keywords: Cancer, taxol, vinblas-tine, vincristine, the camptothecin derivatives.


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