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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

ANTIBACTERIAL AND CYTOTOXIC EFFECTS OF EXTRACTS OF SELECTED MEDICINAL PLANTS OF FAMILY APOCYNACEAE

Viji. M. O*, Neeba Wilson and Iyna Bastian

ABSTRACT

The present study was conducted to evaluate the antibacterial and cyto toxic properties of chloroform, ethyl acetate and methanolic extract of leaves of Nerium indicum, Ichnocarpus frutescens, Tabernaemontana alternifolia, Tabernaemontana divaricata, Catharanthus roseus. The test gave positive results regarding antibacterial activity with inhibition zone diameter ranging from 2mm-17mm. Methanolic extract of the leaves of Tabernaemontana divaricata showed highest activity. In the brine shrimp lethality test all the extract showed significant results. Percentage of lethality was concentration dependent. Percentage of mortality was assessed as LC50 value of the plant extracts which were found to be ranging from 68.2Âµg/ml to 11.3Âµg/ml. The study confirmed antimicrobial and cytotoxic property of the plants and its potential as source of plant based drugs.

Keywords: Nerium indicum, Ichnocarpus frutescens, Tabernaemontana alternifolia, Tabernaemontana divaricata, Catharanthus roseus, antibacterial activity, cyto toxic activity.

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