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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: NOVEMBER ISSUE PUBLISHED

NOVEMBER 2024 Issue has been successfully launched on 1 NOVEMBER 2024.

Abstract

IMMUNOMODULATORY ACTIVITY OF ETHANOL EXTRACT OF THE ASCIDIAN DIDEMNUM ALBIDUM

* G. Ananthan and K. Iyappan

ABSTRACT

The immunomodulatory activity was examined in human monocytic cell line, RAW 264.7. The extract from ascidian activated RAW cells to produce tumor necrosis factor (TNF)-Î± and interleukin (IL)-1Î² and nitric oxide (NO) at dose dependently. While increasing the parameters of macrophage activation, extract inhibited the growth of RAW and induce morphological changes in adherent monocytic cells into macrophages. This study indicated that extract of Didemnum albidum have effect of immunomodulatory activity, hence this extract can be useful to immune system.

Keywords: Ascidian, Didemnum albidum, immunomodulation, macrophage, cytokines.

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