Abstract

A DESCRIPTIVE REVIEW ON TRANSDERMAL PATCHES

Sehrish Hayat*, Ruqayya Nawaz

ABSTRACT

A transdermal patch is a pharmaceutical preparation of different sizes which contains one or more active pharmaceutical ingredient, proposed to be applied on the skin, & after crossing the skin barriers deliver the API to the systemic circulation. Transdermal drug delivery system comes under the group of controlled delivery of the drug and its objective is to transport the active ingredient, in a controlled & predetermined rate, through the skin. Poor bioavailability of traditional oral dosage form due to the hepatic first pass effect is improved by introducing transdermal drug delivery system. This article reviews the various types of transdermal patches, the selection of polymers & drug candidates which are appropriate for the formulation of transdermal System, advantages and disadvantages, future trends and finally its’ evaluation methods.

Keywords: Transdermal Patches, TDDS, Transdermal Drug Delivery System, Skin.