Abstract

SYNTHESIS AND ANTI BACTERIAL ACTIVITY OF ARYL THIAZOLIDIN-4-ONE/AZETIDIN-2-ONE DERIVATIVES FROM PYRIMIDO-BENZIMIDAZOLE

P.Bhaskar, Kumaraswamy Gullapelli, T.Muralikrishna, G.Brahmeshwari*

ABSTRACT

The present study and investigation of synthesis of pyrimido-benzimidazole derivatives were in appreciable yield. The structures of newly synthesized compounds were characterized by 1HNMR, and Mass spectral data. All of the these derivatives were evaluated for their anti bacterial activity against Klebsielia pneumonia, Micrococcus luteus, E.coli Salmonella typhi were showed good to moderate antifungal activity as compared to standard drug Tetracycline.

Keywords: Synthesis, thiazolidines, azetidines, pyrimido benzimidazole derivatives, antibacterial activity.