Abstract

EVALUATION OF ANTI-BACTERIAL AND ANTI CANCEROUS ACTIVITY OF ALANGIUM LAMARCKII LEAF BY METHANOL EXTRACT AGAINST C-6 AND MCF-7 CELL LINES

Mamatha. J* and Oinam Rakeshlal Singh

ABSTRACT

Alangium lamarckki (Akola) commonly found in tropical forest in South India. Akola is a very important medicinal plant and being used as indigenous drugs by the people of village community. The Plant and plant products are the major source for the discovery of new drugs. Alangium lamarckii utilized in traditional medicine has resourceful medicinal properties. In the present study we carried out Crude solvent extraction of leaves of A. lamarckii was performed using a methanol and to evaluate the anti-bacterial activity and anti-cancerous activity of C6 and MCF-7 cell lines by MTT assay. The result suggested that the methanol leaf extract inhibit cell proliferation of both brain cancerous cell line i.e. C6 and MCF-7 which is breast cancerous cell lines.

Keywords: Alangium lamarckii, 5FU, C6, MCF-7, Cell lines, Methonol, Anti-Cancerous activity.