Abstract

INVITRO-ANTIOXIDANT, ANTI INFLAMMATORY AND ANTI PROLIFERATIVE ACTIVITY OF CRUDE EXTRACT OF BACOPA MONNIERI

Bhoomi B. Joshi, Jagdish Patel, Piyush chudasama and Kinnari N Mistry*

ABSTRACT

The study was aimed at evaluating the antioxidant and anti inflammatory activity of crude extract of leaves of Bacopa monnieri (L) Penn. (family: Scrophulariaceae). The antioxidant properties were evaluated using different antioxidant tests such as DPPH scavenging activity, ABTS scavenging activity, superoxide anion radical scavenging, hydrogen peroxide scavenging, free radical scavenging, metal chelating activity and total antioxidant activity along with different anti inflammatory tests such as albumin inhibition activity, membrane stabilization and protein inhibitory activity.The various Antioxidant activity and anti inflammatory activity were compared to synthetic drugs such as ascorbic acid and aspirin. When compared with ethanolic extract methanolic extract showed higher antioxidant and anti-inflammatory effect.

Keywords: Bacopa monnieri, Antioxidant activity, Synergistic effect, Anti-inflammatory activity, inhibitory effect.