Abstract

FORMULATION OF LORNOXICAM ORAL DISINTEGRATING TABLETS

*V.P. Pandey, R. Murugan and Kala Narayana

ABSTRACT

The present work relates to the formulation and evaluation of lornoxicam oral disintegrating tablets, six tablet formulations were tried and among them, one was found suitable for oral disintegrating tablet of lornoxicam in evaluation. Various excipients for taste masking, mouth feel and fast disintegrate of tablets were tried alone or in combination with varying proportions in present study. One formulation with Kyron T- 114, microcrystalline cellulose 102, sodium lauryl sulphate, pearlitol 200 SD, sucralose, banana flavor, dry vanilla, aerosol, magnesium stearate, crospovidone XL 10 and D. M – water was prepared and found suitable in present study. The present study demonstrated lornoxicam as oral disintegrating tablet for better patient compliance.

Keywords: Lornoxicam, oral disintegrating, Kyron T- 114, Excipients, Tablets.