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1,5-BENZOTHIAZEPINE “A VERSATILE NUCLEUSE IN PHARMACEUTICAL FIELD”
Venkata Rao Vutla*, K.N.Rajinikanth, Ramarao Nadendla and Ch. M. M. Prasad
ABSTRACT The 1, 5-benzothiazepine derivatives are of particular interest for lead discovery because they have been found active against different families of targets. The first molecule of 1,5-benzothiazepine used clinically was diltiazem , followed by clentiazem, for their cardiovascular action. Some of the 1,5-benzothiazepine derivatives were also used clinically for CNS disorders which includes thiazesim, clothiapine and quetiapine Keywords: 1,5-benzothiazepines , antidepressant, CNS stimulant, antihypertensive etc. [Download Article] [Download Certifiate] |