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All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
SYNTHESIS, CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY OF THIADIAZOLE DERIVATIVES
Dr Himanshu Sharma*,Prem Shankar Mishra, Rakhi Mishraz
ABSTRACT Thiadiazole and their derivatives have been studied extensively because of their wide range of biological activity. Diverse biological activities, such as antibacterial, anti-inflammatory, and antiviral have been associated with 1,3,4-Thiadiazole derivatives. The synthesis of 1, 3, 4- Thiadiazole derivatives has attracted widespread attention due to their diverse biological activities, including antimicrobial, anti-inflammatory. Therefore, it was decided to synthesize some Thiadiazole derivatives. which are expected to possess anti-inflammatory activity. From screening results, It has been observed that final compounds Anti-inflammatory activity was performed by carrageenan induced rat paw oedema method, it was observed that, compounds TH-1C, TH-1B and TH-1E exhibited significant activity Diclofenac sodium was used as standard for measuring anti-inflammatory activity. Keywords: Thiadiazole, Anti-inflammatory and Antihelminthics. [Download Article] [Download Certifiate] |