Abstract

ANALGESIC, ANTI-INFLAMMATORY ACTIVITY OF PALIPERIDONE IN EXPERIMENTAL ANIMAL MODELS

B. Rambabu, Eswara Rao G, Sunil Junapudi, Maheshwari A, T. Nagasree*

ABSTRACT

The Paliperidone was investigated for its anti-inflammatory and analgesic activities in animal models. The Paliperidone at 5 mg/kg body weight reduced significantly the formation of oedema induced by carrageenan and histamine. In the acetic acid-induced writhing model, hot plate method and tail flick method the Paliperidone had a good analgesic effect (P

Keywords: Anti-inflammatory, Analgesic activities, Diclofenac Sodium, Paliperidone.