Abstract

NIOSOME: AN UNIQUE DRUG DELIVERY SYSTEM

Raju. Manda*, Dr. R. Suthakaran, Virajaji Kaya, Bonagiri Sreedevi,
T. Hurumathfathima

ABSTRACT

The ideal drug delivery system delivers drug at rate dictated by the need of the body over the period of treatment and it channels the active entity solely to the site of action. Niosomes are non-ionic surfactant vesicles obtained on hydration of synthetic nonionic surfactants, with or without incorporation of cholesterol or other lipids. They are vesicular systems similar to liposomes that can be used as carriers of amphiphilic and lipophilic drugs. Niosomes are promising vehicle for drug delivery and being non-ionic, it is less toxic and improves the therapeutic index of drug by restricting its action to target cells. This systemic review article deals with preparation methods, characterizations, factors affecting release kinetic, advantages, and applications of niosomes

Keywords: .