EXTRACTION, ESTIMATION AND THIN LAYER CHROMATOGRAPHY OF FLAVONOIDS: A REVIEW
*Amit Gangwal
Smriti College of Pharmaceutical Education, Indore (M.P.) 452010, India.
ABSTRACT
Since time immemorial flavonoids are in use in various parts of the
world for sure shot treatment or for approximate and rudimentary
treatment of various ailments. They were among the earliest chemicals
isolated in pure form from natural sources. Till date they are the most
fancied natural chemical for scientist of various backgrounds (botanist,
biochemist, pharmacognosist, pharmacologist, natural product chemist
etc), because they are one of the most potent and promising bioactive
chemicals, obtained from natural sources. Various flavonoids have
been reported in literature for range of pharmacological activities.
Worldwide drug discovery is going through a rough patch. Various
models are being discussed, new approaches are emerging, and
synthetic drugs are enjoying good position among available options, still natural sources can
never be undermined, as most of the established drug molecules trace their route to natural
sources directly or indirectly. In this review article an attempt has been made to compile basic
and crucial information (extraction methods, thin layer chromatography and estimation) on
putative secondary metabolite; flavonoids. Compiled information is just and highly concised
and widely reported.
Keywords: Flavonoids, extraction, estimation, TLC, drug discovery, natural products.
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