Abstract

FORMULATION AND EVALUATION OF NAPROXEN EMULGELS FOR TOPICAL DELIVERY

Niraj Kumar* and Maurya Satkar Prasad

ABSTRACT

Topical drug delivery is the “process of applying a medicationcontainingformulation to the skin to treat a cutaneous ailment.” Theapplication of topical treatments like ointments, creams, and lotions isuncomfortable for the patient since they are typically very sticky. Theymust be utilized carefully because they have a reduced spreadingcoefficient. They struggle with stability as well. To solve this issue,transparent gels have grown in popularity in cosmetic andpharmaceutical formulations. The formation of gels results from theconsiderable entrapment of an aqueous or hydroalcoholic liquid in asystem of colloidal solid particles. Gel compositions offer a quickertherapeutic release than ointments and creams. Gels have onefundamental disadvantage despite all of their benefits: they cannotdeliver hydrophobic medications. To get over this restriction, anemulsion-based technique is being created that will efficiently incorporate and deliver ahydrophobic therapeutic component across gels. Emulgels are dosage forms that combine thebenefits of gels and emulsions. Emulsions have a refined appearance and can be readilyremoved from the skin. They also penetrate the skin fairly well. “Emollient, non-staining,water-soluble, easier spread ability, longer shelf life, bio-friendly, translucent, and a pleasinglook are just a few of the benefits of emulgels for dermatological treatment.

Keywords: Topical drug delivery, hydrophobic, Emulgels.