Abstract

ECO-FRIENDLY SILVER NANOPARTICLES FROM TAMARINDUS INDICA: A NOVEL ANTHELMINTIC THERAPY

Apeksha G. Toshniwal*, Prof. Atul S. Pratapwar and Vishal G. Thorat

ABSTRACT

Tamarindus is a monotypic genus and belongs to the subfamily Caesalpinioideae of the family Leguminosae (Fabaceae). The objective of the present work was to evaluate the in-vitro anthelmintic potency of the ethanolic extract of Aerial parts of Tamarindus indica L. using Indian earthworms (Pheretima posthuma). The various concentrations (1-80 mg/ml) of the aqueous, ethanolic extract and nanoparticles were tested in-vitro for anthelmintic potency by determination of time of paralysis and time of death of worm. Piperazine citrate (10 mg/ml) used as standard. The result of present study indicates that the Tamarindus indica L. potentiate paralysis to earthworm and also caused its death after some time. The shortest time of paralysis and time of death was observed at higher dose (80 mg/ml) of ethanolic extract andnanoparticles. Thus, the present study demonstrates that the Tamarindus indica L. as a potent anthelmintic has been confirm as the nanoparticles of ethanolic extracts of aerial parts displayed activity against the earthworms used in study.

Keywords: Tamarindus indica L., paralysis, death of earthworm, nanoparticles.