Abstract

PHYTOCHEMICAL SCREENING AND ANTHELMINTIC ACTIVITY OF WOOD AND LEAVES OF HIBISCUS TILIACEUS LINN.

Vijay Tambe*, Rajendra Bhambar

ABSTRACT

Various helminthes have been common cause of concern and leads many problems to human beings and other animals. From ancient time different plants are known to possess significant anthelmintic activity against these invasive types of worms and can be effectively used in treatment of worm infections. The prime objective of the study was to investigate different types of phytoconstituents present and anthelmintic activity of Hibiscus tiliaceus wood and leaves. Extraction was carried out by continuous hot percolation method in soxhlet apparatus using petroleum ether, ethyl acetate, methanol as solvents for wood powder and petroleum ether, chloroform, ethyl acetate, ethanol as solvents for leaves powder respectively. The extractive values were reported. All the extracts were subjected to phytochemical screening using standards methods for detection of type of phytoconstituents present in them. In-vitro anthelmintic activity was carried out at three different concentrations using Pheretima posthuma as test organism, the parameters like the time of paralysis and the time of death were determined. All the extracts showed significant anthelmintic activity in the dose dependent manner compared to standard drug albendazole. Amongst the extracts petroleum ether extract of wood and ethyl acetate extract of leaves showed good activity. This might due to the presence of secondary metabolites like tannins, saponins and alkaloids in the plant parts which may be responsible for the activity.

Keywords: Phytochemical screening, Hibiscus tiliaceus, anthelmintic activity, Pheretima posthuma.