Abstract

PREVALENCE OF PEPTIC ULCER DISEASE AMONG THE PATIENTS WITH ABDOMINAL PAIN IN A COMMUNITY HOSPITAL AT KATHMANDU

Devindra Kumar Neupane*, Rahi Bikram Thapa*, Rajani Shakya, Badri K.C., Sabin Shrestha and Anuraj Anu

ABSTRACT

Background: Peptic ulcer disease (PUD) is a global health concern affecting the stomach and upper small intestine, especially in developing nations. Often caused by Helicobacter pylori infection and Non-steroidal anti-inflammatory drugs (NSAID) use, despite treatment advancements, it still poses significant morbidity and mortality risks. Objective: This study aims to determine the prevalence of PUD among patients with abdominal pain in a community hospital in Kathmandu, Nepal. Method: A descriptive cross-sectional study was conducted at Stupa Community Hospital, Boudhha, Kathmandu, from February to July 2018. Data were collected from 153 patients diagnosed with PUD out of 1170 patients presenting with abdominal pain. Information was gathered using a pre-tested semi-structured questionnaire and laboratory reports and analyzed using SPSS version 20. Results: The prevalence of PUD among patients with abdominal pain was 13.1%. The majority of respondents (47%) were aged 21-40 years, with females comprising 56.2%. Gastric ulcers were most common (54.2%), followed by duodenal ulcers (40.5%). Helicobacter pylori infection was found in 55.5% of patients. NSAID use was reported by 37.3% of respondents, with 91.2% practicing self-medication. The study reveals that 39.2% of respondents smoke cigarettes, 17.6 % use tobacco. Alcohol consumption is reported by 37.9%, 17.0% have stress-related problems, and 39.9% of respondents have a positive history of PUD. Conclusion: The study highlights the notable prevalence of PUD in abdominal pain patients, emphasizing the need for awareness and targeted interventions. Risk factors like Helicobacter pylori infection and NSAID use need to be addressed for effective management and prevention.

Keywords: Peptic ulcer disease, Helicobacter pylori, endoscopy, Prevalence.