Abstract

ROLE OF 3D BIOPRINTING IN TISSUE ENGINEERING

Ausaf Butool*, Masira Ummul Khair, Zeenath Begum, Y. Rajesh, Anupama Koneru

ABSTRACT

Three-dimensional (3D) printing is the one of the most popular manufacturing processes that combines both technology and biosciences for the fabrications of 3D constructs. It has shown strong potential for the fabrication of bio-structures in the field of tissue engineering, most notably for bones, orthopedic tissues, and associated organs. Desirable biological, structural, and mechanical properties can be achieved for 3D-printed constructs with a proper selection of biomaterials and compatible bio-printing methods. Three-dimensional (3D) printing has attracted increasing interest during the last decades and is already used in various industrial sectors for the rapid and easy fabrication of complex structures and materials. 3D printing, also known as additive manufacturing has also led to remarkable advances in the healthcare sector (3D bio-printing), especially in regenerative medicine, as it facilitates on-demand "printing" of cells, tissues andorgans. These technological advances have led to the creation of new scientific fields such as tissue engineering and is also used in drug delivery and cancer studies. Bio-printing can provide patient-specific spatial geometry, controlled microstructures and the positioning of different cell types for the fabrication of tissue engineering scaffolds. However, future developments are now concentrating on the combining of techniques to work in a complementary fashion to optimize the process of creating tissue mimicking structures.

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