Abstract

BIOEVALUATION OF ALPINIA GALANGA (L.) WILLD FOR ANTI-ALZHEIMER’S ACTIVITY BY USING RAT MODEL

Akanksha D. Patil*, Aniket B. Parate, N. I. Kochar, D. S. Mohale, A. V. Shrirao and A. V. Chandewar

ABSTRACT

A neurodegenerative illness named Alzheimer's disease is characterized by decreased memory and an ongoing decrease in mental abilities. The drug-based treatments available today have an insufficient efficacy rate and are likely to have undesirable side effects. The application of natural products that are available sources for innovative therapies has attracted attention. Alpinia galanga (L.) Willd, a member of the ginger family, has been used for centuries in folk medicine. The goal of this study was to utilize a rat model to examine the anti-Alzheimer's activity of A. galanga leaves extract. The present work was done to study the possible anti-alzheimer’s effect of methanolic extract of A. galanga (L.) Willd (MEAGW) leaves in memory impaired rats.

Keywords: Alpinia galanga (L.) Willd, Acetylcholinesterase, Anti-alzheimer’s activity, Retention Time, Escape Latency, Transfer Latency.