Abstract

DEVELOPMENT, PRELIMINARY EVALUATION AND ASSESSMENT OF EFFICACY OF HERBAL KAJAL

Dr. Kinjal Bipinkumar Gandhi*, Katherene Mary C. Antony*, Blessy S. Joseph, Janvie S. Maria, Vaishnav R. and Nikhil Wilfred

ABSTRACT

Kohl, Kajal, Kajol, or Tiro is an ancient eye cosmetic accentuating and drawing attention to the eyes for enhanced attractiveness. This research work aims to prepare kajal formulations and evaluate its antimicrobial activity. Herbal kajal formulations were made using different metal plates like silver, bronze, copper by using aloe vera and cow ghee and physical parameters like pH and spreadability. The particle size analysis was done using Dynamic Light Scattering (DLS) equipment followed by In-vitro antimicrobial activity against different strains. The finished product is a glossy black with a characteristic odor. The texture was smooth consistency is semisolid. pH of all the prepared formulations was in the range of 6.5-7.5 indicating neutrality. Particle size distribution provided concise summaries on diameter (nm), volume%, and width within limits. Antimicrobial potential against common eye infection-causing strains showed excellent activity, notably against gram -ve and gram +ve species. All the prepared formulations showed adequate efficacy and were found to be safe for use.

Keywords: Kohl, In-vitro antimicrobial activity, Dynamic Light Scattering, Metal plates.