![]() |
|||||||||||||
|
All | Since 2019 | |
Citation | 5450 | 3969 |
h-index | 23 | 20 |
i10-index | 134 | 84 |
A SMART REVIEW ON MICROBEADS FOR GASTRO RENTENTIVE DRUG DELIVERY
Dr. Praveen Kumar Ashok, Dr. Yogita Tyagi, Ms. Hiba Parveen, *Mani Ratnam Bhardwaj
ABSTRACT
The floating tablets of Amoxicillin trihydrate was developed to achieve a site specific drug delivery. The reason for developing Amoxicillin trihydrate as floating drug delivery systems is to treat Helicobacter pylori infections in stomach. It is desirable to treat the infection in the stomach. The dosage form releases more amount of drug in the stomach which offers better therapy than conventional tablets. The main aim of present research work is to develop gastro retentive drug delivery systems of Amoxicillin trihydrate Floating drug delivery system have a bulk density less than gastric fluids and so remains buoyant in the stomach without affecting gastric emptying rate for a prolonged period of time. The impact of Carbopol 940 in HPMC different grades in matrix formation demonstrated in this work. The swelling property and controlled drug release profile also analysed Keywords: Amoxicillin Trihydrate, HPMC E15 LV, HPMC K4M, Carbopol 940, Microspheres, Ionotropic Gelation Method, Ethyl cellulose, Hydroxy propylmethyl cellulose. [Download Article] [Download Certifiate] |