Abstract

NANOARCHITECTURES FOR TARGETED THERAPY: A REVIEW OF CUBOSOMES IN DRUG DELIVERY SYSTEMS

K. Haricharan, T. Reshma and Nawaz Mahammed

ABSTRACT

The review provides an in-depth analysis of cubosomes, a nanostructured lipid-based drug delivery system, and their applications in targeted therapy. Cubosomes exhibit a unique cubic phase morphology composed of lipid bilayers, offering advantages such as enhanced stability, high encapsulation efficiency, and controlled release capabilities. The review discusses the fundamentals of cubosomes, including their definition, structural components, formation methods, and stability considerations. Furthermore, it explores the advantages of cubosomes in drug delivery, focusing on their potential for targeted delivery to specific tissues or cells, improved bioavailability, and controlled release of therapeutic agents. The review also examines the challenges and limitations associated with cubosome technology, such as scalability issues, biocompatibility concerns, and regulatory hurdles. Finally, future perspectives on potential advancements and innovations in cubosome technology, integration with personalized medicine, and recommendations for future research directions are discussed.

Keywords: Cubosomes, targeted therapy, drug delivery, nanostructured lipid carriers, personalized medicine.