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STUDY OF COMPUTER BASED MOLECULAR DOCKING OF CASSIA FISTULA LEAVES
S. B. Ketkale*, S. J. Nitturkar and M. M. Inamdar
ABSTRACT
Aim of present study is to learn the new approaches in the field of computational Chemistry. We studied here Comparative preliminary photochemical screening test of the ethanol extract and aqueous extract of leaves of Cassia fistula obtained by cold maceration process. These study antibacterial assay was performed with the help of cup plate method for ethanolic and aqueous extract. Further molecular docking is carried out for the phytoconstituents of cassia fistula and viral protein. This study helps to investigate novel use of existing molecules. As the cassia has well reported anticancerr, antibacterial, hepatoprotective, antidiabetic activities we reported by the antibacterial assay with ciprofloxacin as standard. For molecular docking we selected viral proteins such as spike protein (7BZ5) and main protease (7BUY) in COVID-19 virus. We used a docking technique to illustrate the Keywords: Yellow Shower, Molecular Docking, Viral Protein, Flavanoides, Antiviral, Antibacterial. [Download Article] [Download Certifiate] |