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REVIEW ON: MIGRAINE IN PATIENTS WITH INFLAMMATORY BOWEL DISORDERS
Vidhate Samiksha B.*, Gaidhane Shital V. and Kale Disha S.
ABSTRACT
Migraine is a chronic and frequently seen primary headache condition that impacts more than 17% of females and 5%-8% of males. The pathophysiology of migraine is intricate and remains incompletely understood. Recent studies have shown a higher prevalence of gastrointestinal (GI) disorders in migraine patients compared to the general population. Several mechanisms related to the gut-brain axis, such as chronic inflammatory responses with inflammatory and vasoactive mediators entering the circulatory system, modulation of the enteric immunological environment by intestinal microbiota, and dysfunction of the autonomic and enteric nervous systems, have been proposed to elucidate these connections. The complete understanding of the intricate mechanisms and pathways associated with the gut-brain axis in migraine remains to be fully clarified. Migraine has been found to be associated with an increased risk of developing inflammatory Keywords: Migraine, Gastrointestinal disorders, Gut-brain axis, Inflammatory bowel disorders, Microbiota, Crohn's disease, Ulcerative Colitis. [Download Article] [Download Certifiate] |