Abstract

REVIEW ON ORGANOGEL AS TOPICAL DELIVERY SYSTEM

Shashikant A. Pawar*, Moreswar P.Patil , Priyanka S. Sadgir, Navneet B. Wankhede

ABSTRACT

A gel may be defined as a semi-solid formulation having an external solvent phase, a polar (organogel) or polar (hydrogel) immobilized within the spaces available of a three dimensional networked structure. Organogel can be prepared by Fluid-Filled fiber mechanism and Solid fiber mechanism. The chemical enhancer used in dermal formulation for permeation of drug through the skin, it may be produce irritation as in chronic application. Organogel does not require use of chemical enhancer for facilitate drug through the skin. Lecithin, Sorbitan ester base or gelatin use for gellating agent. This article gives information about types of organogelator, types of organogel, properties and Evaluation parameter of organogel with application.

Keywords: Topical Delivery System, Organogel, Gel sol transition study, Organogelator.